4-Acetamidobenzene-d4-sulfonyl Chloride

• CAT Number: C000830
• CAS Number: 77435-44-0
• Molecular Formula: C₈H₄D₄ClNO₃S
• Molecular Weight: 237.7
• Purity: ≥95%
• Synonyms: 4-(Acetylamino)benzenesulfonyl-d4 Chloride; 4-(Acetylamino)benzene-2,3,5,6-sulfonyl-d4 Chloride; NSC 127860-d4; ASC-d4; 4-(Acetylamino)phenylsulfonyl-d4 Chloride; p-Acetamidophenylsulfonyl-d4 Chloride; N-Acetylsulfanilyl-d4 Chloride; Dagenan-d4 Chloride; N-(4-Chlorosulfonylphenyl)acetamide-d4
• Solubility: DMSO (Slightly)
• Appearance: Off-White to Light Beige Solid
• Storage: 4°C, Inert atmosphere
• IUPAC Name: 4-acetamido-2,3,5,6-tetradeuteriobenzenesulfonyl chloride
• InChI: InChI=1S/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)/i2D,3D,4D,5D
• InChIKey: GRDXCFKBQWDAJH-QFFDRWTDSA-N
• SMILES: CC(=O)NC1=CC=C(C=C1)S(=O)(=O)Cl

4-Acetamidobenzene-d4-sulfonyl Chloride (Cat No.:C000830) is a deuterium-labeled form of 4-acetamidobenzene sulfonyl chloride, a chemical intermediate used in organic synthesis and medicinal chemistry. The “d4” notation indicates that four hydrogen atoms in the molecule are replaced with deuterium, a stable isotope of hydrogen. This labeling allows for precise isotope tracing in research and analytical applications. 4-Acetamidobenzene-d4-sulfonyl Chloride is used as a labeled reagent in isotope-labeling experiments, aiding in the understanding of reaction mechanisms and the synthesis of labeled compounds for various applications, including pharmaceutical research and drug development.

Reference

Tashiro, T., et al.: Bioorg. Med. Chem., 16, 8896 (2008); Alcalde, E., et al.: J. Med. Chem., 52, 675 (2009);