4-Aminopyridine

• CAT Number: I003792
• CAS Number: 504-24-5
• Molecular Formula: C5H6N2
• Molecular Weight: 94.11
• Purity: ≥95%
• Target: Potassium Channel
• Solubility: water：50 mg/ml； 100 mM in DMSO ；
• Storage: Store at -20C
• IUPAC Name: pyridin-4-amine
• InChI: InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
• InChIKey: NUKYPUAOHBNCPY-UHFFFAOYSA-N
• SMILES: C1=CN=CC=C1N

4-Aminopyridine (CAT: I003792) is a selective voltage-gated potassium channel blocker, specifically targeting Kv1 family channels. By inhibiting potassium efflux, it prolongs action potential duration and enhances synaptic transmission, leading to improved nerve signal conduction. This mechanism makes 4-Aminopyridine highly valuable in the Neurology field, particularly for research on neurological disorders such as multiple sclerosis (MS) and spinal cord injuries. It is used to investigate treatments aimed at improving motor function and reducing symptoms caused by demyelination. 4-Aminopyridine also serves as a tool in neurophysiological studies to explore nerve conduction and synaptic plasticity.