4-Bromobutyryl Chloride

• CAT Number: R030432
• CAS Number: 927-58-2
• Molecular Formula: C4H6BrClO
• Molecular Weight: 185.445
• Purity: ≥95%
• Synonyms: 4-Bromobutanoic Acid Chloride; 4-Bromobutanoyl Chloride; 4-Bromobutyroylic Chloride; γ-Bromobutyryl Chloride; ω-Bromobutanoyl Chloride
• Storage: RT
• IUPAC Name: 4-bromobutanoyl chloride
• InChI: InChI=1S/C4H6BrClO/c5-3-1-2-4(6)7/h1-3H2
• InChIKey: LRTRXDSAJLSRTG-UHFFFAOYSA-N
• SMILES: C(CC(=O)Cl)CBr

4-Bromobutyryl Chloride (CAS 927-58-2) is used as a reagent in the synthesis of Bepotastine (B317000) which is a histamine H1 receptor antagonist. 4-Bromobutyryl Chloride is also used in the preparation of fimbrolide-nitric oxide donor hybrids as potential antimicrobial agents.It is commonly used in chemical synthesis.

Reference

1. Bulletin Of the Korean Chemical Society. 2013;34(2):549-52.A novel synthetic method for bepotastine, a histamine H1 receptor antagonist. Ha TH, Suh KH, Lee GS. 
2.Pak. J. Pharm. Sci. 2019 Nov;32(6):2651-8.α-Glucosidase inhibitory potential and hemolytic evaluation of newly synthesized 3, 4, 5-trisubstituted-1, 2, 4-triazole derivatives.Rasool S, Shah SA, Ashraf M, Jahan B, Lodhi MA, Khan FA.
3.Recueil des Travaux Chimiques des Pays‐Bas. 1973;92(1):20-34.Synthesis of 1, 3‐thiazepines and 1, 3‐benzo [e] thiazepines.Reinhoudt DN.