4-Carboxy Tolbutamide-d9 Ethyl Ester

• CAT Number: R008110
• CAS Number: 1185126-97-9
• Molecular Formula: C13H18N2O5S
• Molecular Weight: 323.41
• Purity: ≥95%
• Synonyms: 4-[[[(Butyl-d9-amino)carbonyl]amino]sulfonyl]-benzoic Acid Ethyl Ester
• Storage: -20°C
• IUPAC Name: methyl 4-(1,1,2,2,3,3,4,4,4-nonadeuteriobutylcarbamoylsulfamoyl)benzoate
• InChI: InChI=1S/C13H18N2O5S/c1-3-4-9-14-13(17)15-21(18,19)11-7-5-10(6-8-11)12(16)20-2/h5-8H,3-4,9H2,1-2H3,(H2,14,15,17)/i1D3,3D2,4D2,9D2
• InChIKey: ZLNXHCAHLBRDBT-ZYWCKPJZSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)NS(=O)(=O)C1=CC=C(C=C1)C(=O)OC

4-Carboxy Tolbutamide-d9 Ethyl Ester（Cat No.:R008110） is a deuterated form of 4-Carboxy Tolbutamide Ethyl Ester, where nine hydrogen atoms are replaced with deuterium. This isotopic enhancement significantly improves the stability and reduces metabolic degradation, making it ideal for detailed pharmacokinetic and metabolic studies. This compound, a metabolite of the antidiabetic drug Tolbutamide, plays a crucial role in understanding the drug’s metabolic pathways in diabetic treatment. The deuterated version provides precise and reliable data for tracing the drug’s breakdown and assessing its bioavailability and disposition in the human body, aiding in optimizing diabetes management.