4-Chloro-8-(trifluoromethoxy)quinoline

• CAT Number: L024514
• CAS Number: 40516-42-5
• Molecular Formula: C10H5ClF3NO
• Molecular Weight: 247.61
• Purity: ≥95%
• IUPAC Name: 4-chloro-8-(trifluoromethoxy)quinoline
• InChI: InChI=1S/C10H5ClF3NO/c11-7-4-5-15-9-6(7)2-1-3-8(9)16-10(12,13)14/h1-5H
• InChIKey: OEFHGIFQRVQFSA-UHFFFAOYSA-N

4-Chloro-8-(trifluoromethoxy)quinoline(CAT: L024514) is a quinoline derivative featuring both a chlorine atom at position 4 and a trifluoromethoxy group at position 8 of the quinoline ring system. This compound is important in medicinal chemistry and pharmaceutical research due to its quinoline backbone, which is commonly found in biologically active molecules, including antimalarial, antibacterial, and anticancer agents. The presence of the trifluoromethoxy group adds significant electron-withdrawing properties, enhancing the compound’s lipophilicity and metabolic stability. 4-Chloro-8-(trifluoromethoxy)quinoline is used as a building block in the synthesis of more complex quinoline-based drugs and can be involved in the development of new therapeutic agents targeting various diseases.