4-DAMP

For research use only. Not for therapeutic Use.

  • CAT Number: R016860
  • CAS Number: 1952-15-4
  • Molecular Formula: C21H26INO2
  • Molecular Weight: 451.34
  • Purity: ≥95%
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4-DAMP is a potent antagonist of M3 receptor and also has a high affinity for the closely-related M5 receptor[1].


Catalog Number R016860
CAS Number 1952-15-4
Synonyms

(1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate;iodide

Molecular Formula C21H26INO2
Purity ≥95%
InChI InChI=1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1
InChIKey WWJHRSCUAQPFQO-UHFFFAOYSA-M
SMILES C[N+]1(CCC(CC1)OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3)C.[I-]
Reference

[1]. Watson N, et al. Comparative pharmacology of recombinant human M3 and M5 muscarinic receptors expressed in CHO-K1 cells. Br J Pharmacol. 1999 May;127(2):590-6.
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