4-Dechloro-4-(4-chlorophenyl) Loperamide

• CAT Number: R057649
• CAS Number: 1391052-94-0
• Molecular Formula: C35H37ClN2O2
• Molecular Weight: 553.143
• Purity: ≥95%
• Synonyms: 4-(4-Chlorobiphenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide; 4-[4-(4-Chlorobiphenyl-4-yl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide; Loperamide Impurity A
• Target: Neuronal Signaling
• Storage: Store at RT
• IUPAC Name: 4-[4-[4-(4-chlorophenyl)phenyl]-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
• InChI: InChI=1S/C35H37ClN2O2/c1-37(2)33(39)35(30-9-5-3-6-10-30,31-11-7-4-8-12-31)23-26-38-24-21-34(40,22-25-38)29-17-13-27(14-18-29)28-15-19-32(36)20-16-28/h3-20,40H,21-26H2,1-2H3
• InChIKey: AYFNODUPEBZSRR-UHFFFAOYSA-N
• SMILES: CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)O)(C4=CC=CC=C4)C5=CC=CC=C5

4-Dechloro-4-(4-chlorophenyl) Loperamide is a synthetic derivative of loperamide, an opioid medication primarily used to treat diarrhea. This compound retains the core structure of loperamide while featuring two chlorine atoms, which may enhance its pharmacological properties. It acts on opioid receptors in the gut to decrease gastrointestinal motility, effectively reducing the frequency of bowel movements. Research into its specific effects and potential applications continues, emphasizing the importance of understanding modified opioids in therapeutic contexts and their safety profiles.