4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2

• CAT Number: R025996
• CAS Number: NA
• Molecular Formula: C₂₈¹³CH₂₅F₇N₂¹⁵N₂O₃
• Molecular Weight: 613.5
• Purity: ≥95%
• Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4’-fluoro-[1,1’-biphenyl]-4-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one-13C, 15N2
• Storage: Store at -20 ℃

4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 is a labeled derivative of aprepitant, an antiemetic drug used to prevent nausea and vomiting caused by chemotherapy. In this compound, specific carbon and nitrogen atoms are replaced with the isotopes carbon-13 and nitrogen-15, respectively. The labeling allows for precise tracking and analysis in pharmacokinetic and metabolic studies using techniques like mass spectrometry. This helps researchers study the drug’s absorption, distribution, metabolism, and excretion, providing valuable insights into its behavior in the body and potential drug interactions.