4-Deoxypodophyllotoxin

• CAT Number: R042074
• CAS Number: 19186-35-7
• Molecular Formula: C22H22O7
• Molecular Weight: 398.41
• Purity: ≥95%
• Synonyms: AS 2-3; Anthricin; Deoxypodophyllotoxin; Desoxypodophyllotoxin; Silicicolin; (-)-Anthricin; (-)-Deoxypodophyllotoxin; (-)-Desoxypodophyllotoxin
• Storage: -20°C
• IUPAC Name: (5R,5aR,8aR)-5-(3,4,5-trimethoxyphenyl)-5a,8,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one
• InChI: InChI=1S/C22H22O7/c1-24-17-6-12(7-18(25-2)21(17)26-3)19-14-8-16-15(28-10-29-16)5-11(14)4-13-9-27-22(23)20(13)19/h5-8,13,19-20H,4,9-10H2,1-3H3/t13-,19+,20-/m0/s1
• InChIKey: ZGLXUQQMLLIKAN-SVIJTADQSA-N
• SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O

4-Deoxypodophyllotoxin（Cat No.:R042074）is a naturally occurring lignan with potent anticancer properties, derived from plants like Podophyllum species. It acts by inhibiting microtubule assembly, disrupting cell division, and inducing apoptosis in cancer cells. This compound shows promising activity against various cancer types, including lung, breast, and colorectal cancers. Additionally, 4-Deoxypodophyllotoxin serves as a precursor for the synthesis of anticancer drugs such as etoposide. Its ability to target rapidly dividing cells makes it a valuable compound in oncology research for developing new therapies with improved efficacy and reduced toxicity.