4-Formylcolchicine

• CAT Number: I042648
• CAS Number: 2730-82-7
• Molecular Formula: C23H25NO7
• Molecular Weight: 427.45
• Purity: ≥95%
• Synonyms: N-[(7S)-4-formyl-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
• InChI: InChI=1S/C23H25NO7/c1-12(26)24-17-8-6-14-16(11-25)21(29-3)23(31-5)22(30-4)20(14)13-7-9-19(28-2)18(27)10-15(13)17/h7,9-11,17H,6,8H2,1-5H3,(H,24,26)/t17-/m0/s1
• InChIKey: JUWAUXATKRGHCK-KRWDZBQOSA-N
• SMILES: CC(=O)N[C@H]1CCC2=C(C(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC)C=O

4-Formylcolchicine（Cat No.:I042648）is a chemical derivative of colchicine, a well-known alkaloid used for its anti-inflammatory and anticancer properties. The modification involves the introduction of a formyl group at the 4-position of the colchicine structure, which may alter its bioactivity and pharmacokinetics. Like colchicine, 4-formylcolchicine has potential therapeutic applications in cancer treatment, particularly in disrupting microtubule dynamics, which are essential for cell division. Additionally, its anti-inflammatory properties could be leveraged in conditions such as gout or arthritis. Further research is needed to explore its full therapeutic potential and possible advantages over colchicine.