For research use only. Not for therapeutic Use.
AC45594 is a steroidogenic factor-1 inverse agonist.
| Catalog Number | M063020 |
| CAS Number | 13037-86-0 |
| Synonyms | 4-(heptyloxy)phenol |
| Molecular Formula | C13H20O2 |
| Purity | ≥95% |
| Target | Bacterial |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | Store at +4C |
| IUPAC Name | 4-heptoxyphenol |
| InChI | InChI=1S/C13H20O2/c1-2-3-4-5-6-11-15-13-9-7-12(14)8-10-13/h7-10,14H,2-6,11H2,1H3 |
| InChIKey | HZBABTUFXQLADL-UHFFFAOYSA-N |
| SMILES | CCCCCCCOC1=CC=C(C=C1)O |
| Reference | </br>1: Mlynarczuk J, Wrobel MH, Kotwica J. The orphan nuclear receptor SF-1 is involved in the effect of PCBs, DDT, and DDE on the secretion of steroid hormones and oxytocin from bovine luteal cells during the estrous cycle in vitro. Theriogenology. 2014 Apr 15;81(7):877-86. doi: 10.1016/j.theriogenology.2014.01.016. PubMed PMID: 24576709.</br>2: Mlynarczuk J, Wrobel MH, Rekawiecki R, Kotwica J. The expression of Steroidogenic Factor-1 and its role in bovine steroidogenic ovarian cells during the estrus cycle and first trimester of pregnancy. Anim Reprod Sci. 2013 Apr;138(1-2):74-81. doi: 10.1016/j.anireprosci.2013.01.008. PubMed PMID: 23481593.</br>3: Doghman M, Cazareth J, Douguet D, Madoux F, Hodder P, Lalli E. Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists. J Clin Endocrinol Metab. 2009 Jun;94(6):2178-83. doi: 10.1210/jc.2008-2163. PubMed PMID: 19318454; PubMed Central PMCID: PMC2690427.</br>4: Del Tredici AL, Andersen CB, Currier EA, Ohrmund SR, Fairbain LC, Lund BW, Nash N, Olsson R, Piu F. Identification of the first synthetic steroidogenic factor 1 inverse agonists: pharmacological modulation of steroidogenic enzymes. Mol Pharmacol. 2008 Mar;73(3):900-8. PubMed PMID: 18055761.</br></br> |
