4-Hydroperoxy Cyclophosphamide

• CAT Number: R005056
• CAS Number: 39800-16-3
• Molecular Formula: C7H15Cl2N2O4P
• Molecular Weight: 293.08
• Purity: ≥95%
• Synonyms: 2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl Hydroperoxide; 4-Hydroperoxycyclofosfamide; Asta 6496
• Target: Apoptosis
• Solubility: 5mg/ml in water, >100 mg/ml in DMSO
• Storage: -20°C, at room temperatur stable for about a week
• InChI: InChI=1S/C7H15Cl2N2O4P/c8-2-4-11(5-3-9)16(13)10-7(15-12)1-6-14-16/h7,12H,1-6H2,(H,10,13)
• InChIKey: VPAWVRUHMJVRHU-UHFFFAOYSA-N
• SMILES: C1COP(=O)(NC1OO)N(CCCl)CCCl

4-Hydroperoxy Cyclophosphamide（Cat No.:R005056）is a stable, active form of the chemotherapeutic agent cyclophosphamide. Unlike cyclophosphamide, which requires metabolic activation in the liver, 4-Hydroperoxy Cyclophosphamide spontaneously converts into its active metabolites in aqueous solutions, making it useful in in vitro studies. It functions as an alkylating agent, cross-linking DNA strands and inducing apoptosis in rapidly dividing cancer cells. This compound is used primarily in cancer research and immunosuppressive therapy, offering a direct way to study cyclophosphamide’s effects without relying on liver metabolism for activation.