4-Hydroxy Flecainide

• CAT Number: R057260
• CAS Number: 152171-74-9
• Molecular Formula: C17H20F6N2O4
• Molecular Weight: 430.347
• Purity: ≥95%
• Synonyms: 4-Hydroxy-N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (±)-4-Hydroxy-N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
• Storage: -20°C
• IUPAC Name: 4-hydroxy-N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
• InChI: InChI=1S/C17H20F6N2O4/c18-16(19,20)8-28-13-6-12(26)14(29-9-17(21,22)23)5-11(13)15(27)25-7-10-3-1-2-4-24-10/h5-6,10,24,26H,1-4,7-9H2,(H,25,27)
• InChIKey: QUXZMOOURSXVFW-UHFFFAOYSA-N
• SMILES: C1CCNC(C1)CNC(=O)C2=CC(=C(C=C2OCC(F)(F)F)O)OCC(F)(F)F

4-Hydroxy Flecainide is a metabolite of flecainide, a medication used primarily to prevent and treat irregular heartbeats such as atrial fibrillation. This metabolite forms through the hepatic metabolism of flecainide, involving the hydroxylation of the parent compound. 4-Hydroxy Flecainide retains some of the antiarrhythmic properties of its parent drug but is generally less potent. Studying this metabolite is important for understanding the pharmacokinetics and dynamics of flecainide, especially in patients with varying metabolic rates.