4-hydroxy Nonenal Glutathione-d3 (trifluoroacetate salt)

• CAT Number: R067450
• Molecular Formula: C19H30D3N3O8S • CF3COOH
• Molecular Weight: 580.6
• Purity: ≥95%
• Synonyms: 4-HNE-GSH-d3
• Storage: -20°C
• InChI: InChI=1S/C19H33N3O8S.C2HF3O2/c1-2-3-4-5-13-14(8-17(26)30-13)31-10-12(18(27)21-9-16(24)25)22-15(23)7-6-11(20)19(28)29;3-2(4,5)1(6)7/h11-14,17,26H,2-10,20H2,1H3,(H,21,27)(H,22,23)(H,24,25)(H,28,29);(H,6,7)/t11?,12-,13?,14-,17?;/m0./s1/i1D3
• InChIKey: HORQSLGDIZDKSI-YQIWDRHISA-N
• SMILES: O=C(NCC(O)=O)[C@H](CS[C@H]1CC(O)OC1CCCCC([2H])([2H])[2H])NC(CC[C@@H](N)C(O)=O)=O.FC(F)(C(O)=O)F

4-Hydroxy Nonenal Glutathione-d3 (trifluoroacetate salt) is a deuterated compound vital for advanced biochemical and pharmaceutical research. Featuring three deuterium atoms, it provides enhanced stability and precision in mass spectrometry and NMR spectroscopy. This isotopically labeled analog is crucial for studying the detoxification pathways of lipid peroxidation products and oxidative stress. It ensures accurate quantification and reliable analytical results, making it an ideal standard for high-precision research in cellular metabolism, oxidative damage, and the investigation of antioxidant defense mechanisms.

Reference

1.Pryor, W.A., and Porter, N.A. Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. Free Radical Biology & Medicine 8, 541-543 (1990).