4-Hydroxy Propafenone-d5 Hydrochloride

• CAT Number: R008293
• CAS Number: 1189863-32-8
• Molecular Formula: C21H28ClNO4
• Molecular Weight: 398.939
• Purity: ≥95%
• Synonyms: 1-[4-Hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenl]-3-phenyl-1-propanone-?d5 Hydrochloride
• Storage: -20°C
• IUPAC Name: 1-[4-hydroxy-2-[1,1,2,3,3-pentadeuterio-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride
• InChI: InChI=1S/C21H27NO4.ClH/c1-2-12-22-14-18(24)15-26-21-13-17(23)9-10-19(21)20(25)11-8-16-6-4-3-5-7-16;/h3-7,9-10,13,18,22-24H,2,8,11-12,14-15H2,1H3;1H/i14D2,15D2,18D
• InChIKey: WKRSKHMUIJZGKZ-CHHLNNTKSA-N
• SMILES: [2H]C([2H])(C([2H])(C([2H])([2H])OC1=C(C=CC(=C1)O)C(=O)CCC2=CC=CC=C2)O)NCCC.Cl

4-Hydroxy Propafenone-d5 Hydrochloride is a deuterated form of 4-hydroxy propafenone hydrochloride, an active metabolite of the antiarrhythmic drug propafenone. The deuterium labeling, with five deuterium atoms, makes it an ideal compound for pharmacokinetic and metabolic studies. It is used in pharmaceutical research to investigate the metabolism, distribution, and excretion of propafenone. This isotopically labeled compound helps in understanding the drug’s bioavailability and interactions, aiding in the optimization of dosing regimens and the development of safer, more effective antiarrhythmic therapies.