4’-Hydroxy Tamoxifen-d6 (contains up to 10percent E isomer)

• CAT Number: R051403
• CAS Number: 1346606-80-1
• Molecular Formula: C26H29NO2
• Molecular Weight: 393.56
• Purity: ≥95%
• Synonyms: 4-[(1Z)-1-[[4-[2-(Dimethylamino-d6)ethoxy]phenyl]phenylmethylene]propyl]phenol;?4’-Hydroxytamoxifen-d6
• Storage: 3 years -20C powder
• IUPAC Name: 4-[(Z)-1-[4-[2-[bis(trideuteriomethyl)amino]ethoxy]phenyl]-1-phenylbut-1-en-2-yl]phenol
• InChI: InChI=1S/C26H29NO2/c1-4-25(20-10-14-23(28)15-11-20)26(21-8-6-5-7-9-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-/i2D3,3D3
• InChIKey: DODQJNMQWMSYGS-JIVKCLLGSA-N
• SMILES: [2H]C([2H])([2H])N(CCOC1=CC=C(C=C1)/C(=C(/CC)\C2=CC=C(C=C2)O)/C3=CC=CC=C3)C([2H])([2H])[2H]

4’-Hydroxy Tamoxifen-d6, containing up to 10% E isomer（Cat No.:R051403）, is a deuterated version of 4’-Hydroxy Tamoxifen, where six hydrogen atoms are replaced with deuterium. This isotopic enhancement increases its chemical stability and precision in analytical settings, making it crucial for studying the metabolism and pharmacokinetics of Tamoxifen, a key drug in breast cancer treatment. The presence of the E isomer provides insights into the isomerization that can affect drug efficacy and safety. This deuterated compound is used extensively in research to develop more effective cancer therapies and to understand Tamoxifen’s action mechanism more comprehensively.