4-Hydroxyatomoxetine-d3

• CAT Number: S000478
• CAS Number: 1217686-14-0
• Molecular Formula: C17H18D3NO2
• Molecular Weight: 274.37
• Purity: ≥95%
• IUPAC Name: 3-methyl-4-[(1R)-1-phenyl-3-(trideuteriomethylamino)propoxy]phenol
• InChI: InChI=1S/C17H21NO2/c1-13-12-15(19)8-9-16(13)20-17(10-11-18-2)14-6-4-3-5-7-14/h3-9,12,17-19H,10-11H2,1-2H3/t17-/m1/s1/i2D3
• InChIKey: PPXQPRLGNSJNJM-NVNSKBCASA-N
• SMILES: CC1=C(C=CC(=C1)O)OC(CCNC)C2=CC=CC=C2

4-Hydroxyatomoxetine-d3（Cat No.:S000478） is a deuterated form of 4-hydroxyatomoxetine, where three hydrogen atoms are replaced with deuterium. This modification enhances the study of the compound’s pharmacokinetics and stability in the body. 4-Hydroxyatomoxetine is a major active metabolite of atomoxetine, a medication primarily used to treat attention deficit hyperactivity disorder (ADHD). It works by inhibiting the reuptake of norepinephrine, thereby increasing its availability in the brain. The deuterated version, 4-Hydroxyatomoxetine-d3, helps researchers investigate how deuteration impacts the metabolism and effectiveness of the drug, providing valuable insights into its therapeutic properties.