4'-Methylchrysoeriol

• CAT Number: I019757
• CAS Number: 4712-12-3
• Molecular Formula: C17H14O6
• Molecular Weight: 314.29
• Purity: ≥95%
• Synonyms: 2-(3,4-dimethoxyphenyl)-5,7-dihydroxychromen-4-one
• InChI: InChI=1S/C17H14O6/c1-21-13-4-3-9(5-15(13)22-2)14-8-12(20)17-11(19)6-10(18)7-16(17)23-14/h3-8,18-19H,1-2H3
• InChIKey: AOLOMULCAJQEIG-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)OC

4′-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.
4′-Methylchrysoeriol (34DM57DHF) is a potent inhibitor of P450 enzymes, particularly for P450 1B1, with an IC50 of 19 nM for human P450 1B1-dependent EROD[1].

Reference

[1]. Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res To
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