4-Methylumbelliferone

• CAT Number: R000266
• CAS Number: 90-33-5
• Molecular Formula: C10H8O3
• Molecular Weight: 176.17
• Purity: ≥95%
• Synonyms: 7-Hydroxy-4-methylcoumarin; 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one; 7-Hydroxy-4-methyl-coumarin; 7-Hydroxy-4-methyl-2-chromenone; 7-Hydroxy-4-methyl-2-oxo-3-chromene; 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one; NSC 19026; NSC 9408; Omega 127; Pilot 4
• Target: Disease Research Fields
• Storage: 3 years -20C powder
• InChI: InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
• InChIKey: HSHNITRMYYLLCV-UHFFFAOYSA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)O

4-Methylumbelliferone (also known as hymecromone) is a coumarin derivative commonly used as a fluorescent probe in biochemical assays. It exhibits strong fluorescence under UV light when its hydroxyl group is cleaved, making it useful for detecting enzyme activity, particularly in assays involving glycosidases and esterases. Beyond its role in research, 4-methylumbelliferone has shown potential therapeutic effects as a hyaluronic acid synthesis inhibitor, with applications in treating diseases like cancer and fibrosis. It has also been studied for its anti-inflammatory, antitumor, and hepatoprotective properties, making it a compound of interest in both research and clinical studies.