For research use only. Not for therapeutic Use.
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
| Catalog Number | R000276 |
| CAS Number | 18997-57-4 |
| Synonyms | 7-(β-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one; 4-Methylumbelliferyl Glucopyranoside; Glc1-b-4MU; |
| Molecular Formula | C16H18O8 |
| Purity | ≥95% |
| Storage | -20°C |
| InChIKey | YUDPTGPSBJVHCN-YMILTQATSA-N |
