For research use only. Not for therapeutic Use.
4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions[1][2].
| Catalog Number | R046158 |
| CAS Number | 17695-48-6 |
| Synonyms | (4-methyl-2-oxochromen-7-yl) hexadecanoate |
| Molecular Formula | C26H38O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H38O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(27)29-22-17-18-23-21(2)19-26(28)30-24(23)20-22/h17-20H,3-16H2,1-2H3 |
| InChIKey | QKQVFFACWLFRRX-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C |
| Reference | [1]. Zhi H, et al. Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsule. Journal of Spectroscopy, 2013, 2013. [2]. Dairaku T, et al. Nishimura M, Endo M, Ohashi T, Eto Y. A practical fluorometric assay method to measure lysosomal acid lipase activity in dried blood spots for the screening of cholesteryl ester storage disease and Wolman disease. Mol Genet Metab. 2014 Feb;111(2):193-6. |
