For research use only. Not for therapeutic Use.
4-Methylumbelliferyl N-acetyl-α-D-neuraminic acid (4-MUNANA)(Cat No.:R000274)is a fluorogenic substrate widely used in neuraminidase (sialidase) activity assays for virology, enzymology, and drug discovery. It consists of a 4-methylumbelliferyl (4-MU) fluorophore linked to N-acetylneuraminic acid (sialic acid), which releases fluorescence upon enzymatic cleavage. This makes it an essential tool in influenza virus research, antiviral drug screening, and bacterial neuraminidase studies. Due to its high sensitivity and specificity, 4-MUNANA is frequently employed in biochemical assays, pharmaceutical research, and clinical diagnostics to evaluate neuraminidase inhibitors and viral activity.
CAS Number | 76204-02-9 |
Synonyms | sodium;(2S,4S,5R,6R)-5-acetamido-4-hydroxy-2-(4-methyl-2-oxochromen-7-yl)oxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate |
Molecular Formula | C21H24NNaO11 |
Purity | ≥95% |
IUPAC Name | sodium;(2R,4S,5R,6R)-5-acetamido-4-hydroxy-2-(4-methyl-2-oxochromen-7-yl)oxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate |
InChI | InChI=1S/C21H25NO11.Na/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);/q;+1/p-1/t13-,14+,17+,18+,19+,21-;/m0./s1 |
InChIKey | NNNXBDLJYKMDAI-BUIQBYSTSA-M |
SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)O[C@]3(C[C@@H]([C@H]([C@@H](O3)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)[O-].[Na+] |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |