4-Nitrophenyl 4-guanidinobenzoate hydrochloride

• CAT Number: M084984
• CAS Number: 19135-17-2
• Molecular Formula: C14H13ClN4O4
• Molecular Weight: 336.73
• Purity: ≥95%
• Synonyms: (4-nitrophenyl) 4-(diaminomethylideneamino)benzoate;hydrochloride
• InChI: InChI=1S/C14H12N4O4.ClH/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21;/h1-8H,(H4,15,16,17);1H
• InChIKey: PKSBDZOBYIKNGY-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C(=O)OC2=CC=C(C=C2)[N+](=O)[O-])N=C(N)N.Cl

4-Nitrophenyl 4-guanidinobenzoate (NPGB) hydrochloride is a potent sperm acrosin inhibitor, and also a trypsin substrate[1].

Reference

[1]. J M Kaminski, et al. Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates. J Med Chem. 1986 Apr;29(4):514-9.
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