4'-O-Demethyl-pantoprazole sulfide

• CAT Number: C000771
• CAS Number: 141854-21-9
• Molecular Formula: C₁₅H₁₃F₂N₃O₃S
• Molecular Weight: 353.34
• Purity: ≥95%
• Synonyms: 2-[[[6-(Difluoromethoxy)-1H-benzimidazol-2-yl]thio]methyl]-3-methoxy-4-pyridinol
• Solubility: DMSO (Sparingly), Methanol (Slightly)
• Appearance: Off-White to Pale Brown Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: 2-[[6-(difluoromethoxy)-1H-benzimidazol-2-yl]sulfanylmethyl]-3-methoxy-1H-pyridin-4-one
• InChI: InChI=1S/C15H13F2N3O3S/c1-22-13-11(18-5-4-12(13)21)7-24-15-19-9-3-2-8(23-14(16)17)6-10(9)20-15/h2-6,14H,7H2,1H3,(H,18,21)(H,19,20)
• InChIKey: ILLQTAPXYCRJRB-UHFFFAOYSA-N
• SMILES: COC1=C(NC=CC1=O)CSC2=NC3=C(N2)C=C(C=C3)OC(F)F

4′-O-Demethyl-pantoprazole sulfide (Cat No.:C000771) is a chemical compound derived from pantoprazole, a proton pump inhibitor used to reduce stomach acid production. The compound’s structure suggests a modification involving the removal of a methyl group and the introduction of a sulfide moiety. Researchers likely study its impact on acid secretion pathways and potential therapeutic applications. Investigations into its proton pump inhibition, effects on gastric pH, and its role in acid-related gastrointestinal disorders could contribute to the understanding of its pharmacological properties and potential benefits in managing conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers.

Reference

Peng, C.C., et al.: Handbook of Metabolic Pathways of Xenobiotics, 5, 1953-56 (2014);