For research use only. Not for therapeutic Use.
2,2,6,6-<wbr></wbr>Tetramethylpiperidin-<wbr></wbr>1-<wbr></wbr>oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-<wbr></wbr>oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy. TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.
| Catalog Number | R002434 |
| CAS Number | 2896-70-0 |
| Synonyms | 4-Oxo-2,2,6,6-tetramethyl-1-piperidinyloxy |
| Molecular Formula | C9H16NO2 |
| Purity | ≥95% |
| Storage | -20°C |
| InChIKey | WSGDRFHJFJRSFY-UHFFFAOYSA-N |
