4-Phenylbutyric Acid

• CAT Number: R048396
• CAS Number: 1821-12-1
• Molecular Formula: C10H12O2
• Molecular Weight: 164.20
• Purity: ≥95%
• Synonyms: Benzenebutanoic Acid; 4-Phenyl-n-butyric Acid; γ-Phenylbutanoic Acid; NSC 295
• Storage: RT
• IUPAC Name: 4-phenylbutanoic acid
• InChI: InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)
• InChIKey: OBKXEAXTFZPCHS-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CCCC(=O)O

4-Phenylbutyric acid (Cat No.:R048396), also known as Benzenebutyric acid, is a histone deacetylase (HDAC) inhibitor that plays a significant role in regulating hepatic hepcidin against HCV (Hepatitis C virus). By inhibiting HDAC, it modulates the acetylation of histones, leading to changes in gene expression and epigenetic regulation. Furthermore, 4-Phenylbutyric acid exhibits anti-inflammatory effects by modulating endoplasmic reticulum (ER) stress and autophagy in an acute lung injury model induced by LPS (lipopolysaccharide). Its diverse properties make it a potential candidate for various therapeutic applications, including hepatic and inflammatory conditions.