4-Pyridoxic acid-d3

• CAT Number: S000991
• CAS Number: 1435934-03-4
• Molecular Formula: C8H6D3NO4
• Molecular Weight: 186.18
• Purity: ≥95%

4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine[1][2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Sharma SK, et al. Determination of vitamin B6 vitamers and pyridoxic acid in biological samples. J Chromatogr. 1992 Jul 1;578(1):45-51.
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