4-Thiothymidine

For research use only. Not for therapeutic Use.

  • CAT Number: I041244
  • CAS Number: 7236-57-9
  • Molecular Formula: C10H14N2O4S
  • Molecular Weight: 258.29
  • Purity: ≥95%
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4-Thiothymidine(Cat No.:I041244)is a thymidine analog in which a sulfur atom replaces the oxygen atom at the 4-position of the thymine base. This modification alters its ability to interact with DNA, making it useful for studying DNA replication, repair, and mutagenesis. 4-Thiothymidine can be incorporated into growing DNA strands, where it can induce DNA damage or interfere with cellular processes such as nucleotide excision repair. It is used in research to explore mechanisms of DNA synthesis, mutations, and the development of new therapeutic strategies, especially in cancer and antiviral research.


CAS Number 7236-57-9
Synonyms

1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-4-sulfanylidenepyrimidin-2-one

Molecular Formula C10H14N2O4S
Purity ≥95%
IUPAC Name 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-4-sulfanylidenepyrimidin-2-one
InChI InChI=1S/C10H14N2O4S/c1-5-3-12(10(15)11-9(5)17)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChIKey AVKSPBJBGGHUMW-XLPZGREQSA-N
SMILES CC1=CN(C(=O)NC1=S)[C@H]2C[C@@H]([C@H](O2)CO)O

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