4,4-Difluoropiperidin-3-ol hydrochloride

• CAT Number: L028208
• CAS Number: 1186688-54-9
• Molecular Formula: C5H10ClF2NO
• Molecular Weight: 173.59
• Purity: ≥95%
• IUPAC Name: 4,4-difluoropiperidin-3-ol;hydrochloride
• InChI: InChI=1S/C5H9F2NO.ClH/c6-5(7)1-2-8-3-4(5)9;/h4,8-9H,1-3H2;1H
• InChIKey: QAPULPLRJGHBBX-UHFFFAOYSA-N
• SMILES: C1CNCC(C1(F)F)O.Cl

4,4-Difluoropiperidin-3-ol hydrochloride（Cat No.:L028208）is a fluorinated piperidine derivative, notable for its incorporation of two fluorine atoms and a hydroxyl group. This structure enhances its chemical stability and lipophilicity, making it a useful intermediate in medicinal chemistry. The presence of fluorine atoms increases its metabolic stability and potential for crossing biological membranes, important for developing central nervous system drugs. Its hydroxyl group allows for further functionalization, broadening its utility in synthesizing more complex derivatives. The hydrochloride salt form improves its solubility, facilitating its use in various pharmaceutical formulations.