For research use only. Not for therapeutic Use.
4′,5′-Didehydro-5′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Catalog Number | I041265 |
| CAS Number | 14365-63-0 |
| Synonyms | 1-[(2R,3S)-3,4-dihydroxy-5-methylideneoxolan-2-yl]pyrimidine-2,4-dione |
| Molecular Formula | C9H10N2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C9H10N2O5/c1-4-6(13)7(14)8(16-4)11-3-2-5(12)10-9(11)15/h2-3,6-8,13-14H,1H2,(H,10,12,15)/t6?,7-,8+/m0/s1 |
| InChIKey | WMIBCMZGMYGWHB-ZHFSPANRSA-N |
| SMILES | C=C1C(C(C(O1)N2C=CC(=O)NC2=O)O)O |
| Reference | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
