4BP-TQS

• CAT Number: I010922
• CAS Number: 360791-49-7
• Molecular Formula: C18H17BrN2O2S
• Molecular Weight: 405.31
• Purity: ≥95%
• Synonyms: 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
• InChI: InChI=1S/C18H17BrN2O2S/c19-12-6-4-11(5-7-12)18-15-3-1-2-14(15)16-10-13(24(20,22)23)8-9-17(16)21-18/h1-2,4-10,14-15,18,21H,3H2,(H2,20,22,23)
• InChIKey: YNCXHXYZTLIZTO-UHFFFAOYSA-N
• SMILES: C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=C(C=C4)Br

4BP-TQS is a potent allosteric agonist of α7 nAChR. 4BP-TQS activates nAChRs via an allosteric transmembrane site[1].

Reference

[1]. Gill JK, et al. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2011;108(14):5867-5872.
 [Content Brief]