4E1RCat

• CAT Number: I003172
• CAS Number: 328998-25-0
• Molecular Formula: C28H18N2O6
• Molecular Weight: 478.50
• Purity: ≥95%
• Synonyms: eIF4E/eIF4G Interaction Inhibitor II
• Target: eIF4E/eIF4G inhibitor
• Solubility: 10 mM in DMSO
• Storage: -20°C
• IC50: 3.2 uM
• InChI: InChI=1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-16-
• InChIKey: BBQRBOIMSKMFFO-PGMHBOJBSA-N
• SMILES: O=C1/C(C=C(C2=CC=CC=C2)N1C3=CC=C(C(O)=O)C=C3)=CC4=CC=C(C5=CC=C([N+]([O-])=O)C=C5)O4

4E1RCat（Cat No.:I003172）is a highly efficient catalyst utilized in organic synthesis, particularly for facilitating carbon-carbon bond formation reactions. This chiral, bifunctional catalyst is renowned for its ability to promote asymmetric transformations, making it essential in the development of enantiomerically pure compounds. Its unique structure allows for precise control over reaction pathways, enhancing selectivity and yield. Commonly employed in the synthesis of pharmaceuticals and complex organic molecules, 4E1RCat significantly streamlines the synthetic process, providing researchers with a robust tool for creating diverse and valuable chemical entities in a variety of applications.

Reference

[1]. Liao G, et al. Immediate translation of Formin DIAPH1 mRNA after its exiting the nucleus is required for its perinuclear localization in fibroblasts. PLoS One. 2013 Jun 28;8(6):e68190.