(4S)-1-Fmoc-4-methyl-L-proline

• CAT Number: L002901
• CAS Number: 1228577-03-4
• Molecular Formula: C21H21NO4
• Molecular Weight: 351.41
• Purity: ≥95%
• IUPAC Name: (2S,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-methylpyrrolidine-2-carboxylic acid
• InChI: InChI=1S/C21H21NO4/c1-13-10-19(20(23)24)22(11-13)21(25)26-12-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,13,18-19H,10-12H2,1H3,(H,23,24)/t13-,19-/m0/s1
• InChIKey: BMGFKWBYQPNFGZ-DJJJIMSYSA-N

(4S)-1-Fmoc-4-methyl-L-proline(CAT: L002901) is a derivative of the amino acid L-proline, featuring a methyl group at the 4th position and a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the nitrogen atom. The (4S) stereochemistry ensures the specific 3D arrangement of the molecule, which is essential for peptide synthesis, where chirality plays a crucial role in biological activity. The Fmoc group is commonly used in solid-phase peptide synthesis (SPPS) as a temporary protecting group for the amine, easily removed under mild basic conditions. This compound is valuable in the synthesis of peptides and proteins, particularly in medicinal and biochemical research, where proline-containing sequences are important for protein folding and function.