(4S,4'S)-2,2'-(Cyclobutane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)

For research use only. Not for therapeutic Use.

  • CAT Number: L003105
  • CAS Number: 298693-02-4
  • Molecular Formula: C18H30N2O2
  • Molecular Weight: 306.41
  • Purity: ≥95%
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(4S,4’S)-2,2′-(Cyclobutane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)(CAT: L003105) is a chiral bis-oxazoline ligand commonly used in asymmetric synthesis and catalysis. This compound features two oxazoline rings linked through a cyclobutane core, providing rigidity and a well-defined chiral environment. The tert-butyl groups at the 4-position of each oxazoline ring add steric bulk, enhancing the ligand’s selectivity and effectiveness in chiral catalytic processes, such as asymmetric hydrogenation and Diels-Alder reactions. Its specific (4S,4’S) stereochemistry plays a critical role in facilitating enantioselective transformations, making it valuable in producing optically pure compounds, especially in pharmaceutical synthesis. This bis-oxazoline ligand is widely applied in organic chemistry for achieving high enantioselectivity and efficiency in catalytic systems.


Catalog Number L003105
CAS Number 298693-02-4
Molecular Formula C18H30N2O2
Purity ≥95%
IUPAC Name (4S)-4-tert-butyl-2-[1-[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]cyclobutyl]-4,5-dihydro-1,3-oxazole
InChI InChI=1S/C18H30N2O2/c1-16(2,3)12-10-21-14(19-12)18(8-7-9-18)15-20-13(11-22-15)17(4,5)6/h12-13H,7-11H2,1-6H3/t12-,13-/m1/s1
InChIKey MUPPKWUWZUIUGE-CHWSQXEVSA-N

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