5(6)-TAMRA SE

• CAT Number: I013812
• CAS Number: 246256-50-8
• Molecular Formula: C₂₉H₂₅N₃O₇
• Molecular Weight: 527.52
• Purity: ≥95%
• Target: DNA Stain
• Solubility: DMSO: < 10 mg/mL
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3',6'-bis(dimethylamino)-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate;(2,5-dioxopyrrolidin-1-yl) 3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylate
• InChI: InChI=1S/2C29H25N3O7/c1-30(2)17-6-9-21-23(14-17)37-24-15-18(31(3)4)7-10-22(24)29(21)20-8-5-16(13-19(20)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34;1-30(2)17-6-9-20-23(14-17)37-24-15-18(31(3)4)7-10-21(24)29(20)22-13-16(5-8-19(22)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h2*5-10,13-15H,11-12H2,1-4H3
• InChIKey: UWQYEQKHQZYMMZ-UHFFFAOYSA-N
• SMILES: CN(C)C1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)C(=O)ON5C(=O)CCC5=O)C(=O)O3)C6=C(O2)C=C(C=C6)N(C)C.CN(C)C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(C)C)C5=C(C=CC(=C5)C(=O)ON6C(=O)CCC6=O)C(=O)O3

5(6)-TAMRA SE (Cat No.:I013812) is a fluorescent dye used in molecular biology and biochemistry for labeling and detection applications. It contains a succinimidyl ester group, which reacts with amine groups (–NH2) on proteins, peptides, or other biomolecules to form stable covalent bonds, allowing the fluorescence of TAMRA to be used for imaging and quantification. This compound is often utilized in techniques such as fluorescence microscopy, flow cytometry, and enzyme-linked immunosorbent assays (ELISA). Its bright fluorescence properties make it useful for tracking and studying biomolecular interactions and cellular processes.

Reference

[1]. Fuller ME, et al. Application of a vital fluorescent staining method for simultaneous, near-real-time concentration monitoring of two bacterial strains in an Atlantic coastal plain aquifer in Oyster, Virginia. Appl Environ Microbiol. 2004 Mar;70(3):1680-7.[2]. Brunner A, et al. Labelling peptides with fluorescent probes for incorporation into degradable polymers. Eur J Pharm Biopharm. 1998 May;45(3):265-73.[3]. Jiang M, et al. Design and synthesis of new acid cleavable linkers for DNA sequencing by synthesis. Nucleosides Nucleotides Nucleic Acids. 2014;33(12):774-85.