5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt

• CAT Number: C000035
• CAS Number: 6884-89-5
• Molecular Formula: C₉H₁₃N₄Na₂O₈P
• Molecular Weight: 382.17
• Purity: ≥95%
• Synonyms: 5(4)-Amino-4(5)-imidazolecarboxamide Riboside 5′-Phosphoric Acid Disodium Salt; Sodium ((2R,3S,4R,5R)-5-(5-Amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl Phosphate
• Solubility: Methanol (Slightly), Water (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Inert atmosphere

5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt(CAT: C000035) is disodium salt form of 5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate , which causes accumulation of monophosphorylated derivative 5-aminoimidaz ole-4-carboxamide ribonucleoside (ZMP) and consequent phosphorylation and activation of AMP-activated protein kinase (AMPK).

Reference

Corton, J., et al.: Eur. J. Biochem., 229, 558 (1995); Towler, M., Hardie, D.: Circ. Res., 100, 328 (2007); Narkar, V., et al.: Cell, 134, 405 (2008);