For research use only. Not for therapeutic Use.
5-<wbr></wbr>APDB is an entactogen belonging to the amphetamine and the phenethylamine classes. It is an analog of MDA where the heterocyclic 3-<wbr></wbr>position oxygen from the 3,4-<wbr></wbr>methylenedioxy ring has been replaced by a methylene group. 5-<wbr></wbr>APDB can inhibit serotonin, dopamine and norepinephrine reuptake with IC<sub>50</sub> values of 0.13, 7.1, and 3.2 µM, respectively, and generalizes closely to the non-<wbr></wbr>stimulant MDMA analogs, MBDB and MMAI, in drug discrimination studies. This product is intended for forensic purposes.
| Catalog Number | R058840 |
| CAS Number | 152623-94-4 |
| Synonyms | 5-(2-Aminopropyl)-2,3-dihydrobenzofuran;EMA-4;3-desoxy-MDA |
| Molecular Formula | C11H16ClNO |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 1-(2,3-dihydro-1-benzofuran-5-yl)propan-2-amine;hydrochloride |
| InChI | InChI=1S/C11H15NO.ClH/c1-8(12)6-9-2-3-11-10(7-9)4-5-13-11;/h2-3,7-8H,4-6,12H2,1H3;1H |
| InChIKey | BZKLFXQUBIRXAK-UHFFFAOYSA-N |
| SMILES | CC(CC1=CC2=C(C=C1)OCC2)N.Cl |
| Reference | 1.Monte, A.P.,Marona-Lewicka, D.,Cozzi, N.V., et al. Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine. Journal of Medicinal Chemistry 36, 3700-3706 (1993). |
