5-Azido Uridine

• CAT Number: R050687
• CAS Number: 1355028-82-8
• Molecular Formula: C9H11N5O6
• Molecular Weight: 285.216
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 5-azido-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• InChI: InChI=1S/C9H11N5O6/c10-13-12-3-1-14(9(19)11-7(3)18)8-6(17)5(16)4(2-15)20-8/h1,4-6,8,15-17H,2H2,(H,11,18,19)/t4-,5-,6-,8-/m1/s1
• InChIKey: VOPROYOABONMOS-UAKXSSHOSA-N
• SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)N=[N+]=[N-]

5-Azido Uridine is a modified nucleoside, where the azido group (-N₃) is attached to the 5-position of the uridine base. This structural modification is widely used in biochemical and molecular biology research, particularly in studying RNA synthesis and function. The azido group allows for bioorthogonal labeling, often used in “click chemistry” reactions to tag or modify RNA molecules without disturbing their natural functions. 5-Azido Uridine is a useful tool in nucleic acid research, aiding in the investigation of RNA-protein interactions, RNA synthesis, and the development of therapeutic nucleotides for antiviral or anticancer therapies.