5-ClTEP

• CAT Number: I020952
• CAS Number: 900779-63-7
• Molecular Formula: C12H8ClN5O2
• Molecular Weight: 289.68
• Purity: 98%
• Synonyms: 5-ClTEP; 5 ClTEP; 5ClTEP
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1-(5-Chloro-1H-indol-2-yl)-3-(2H-tetrazol-5-yl)propane-1,3-dione
• InChI: InChI=1S/C12H8ClN5O2/c13-7-1-2-8-6(3-7)4-9(14-8)10(19)5-11(20)12-15-17-18-16-12/h1-4,14H,5H2,(H,15,16,17,18)
• InChIKey: CAMPDSCIVYOSOC-UHFFFAOYSA-N
• SMILES: O=C(C(N1)=CC2=C1C=CC(Cl)=C2)CC(C3=NNN=N3)=O

5-ClTEP(CAT: I020952) is a novel HIV-1 integrase inhibitor that targets the catalytic activity of the integrase enzyme, a critical component in the integration of viral DNA into the host genome. By inhibiting this enzyme, 5-ClTEP effectively blocks a key step in the HIV replication cycle, preventing the establishment of infection in host cells. Its mechanism of action makes it a valuable tool in antiviral research, particularly in studying HIV replication dynamics and developing integrase-targeted therapeutics. 5-ClTEP supports investigations into drug resistance mechanisms and the optimization of combination therapies for improved HIV treatment outcomes.