For research use only. Not for therapeutic Use.
5-Deamino-5-oxo Amiloride Hydrochloride(CAT: C000121) is a compound of significance in the field of ion channel research. It is derived from amiloride, a well-known diuretic and inhibitor of epithelial sodium channels. In this specific form, it acts as an inhibitor of the acid-sensing ion channel-3 (ASIC3). Acid-sensing ion channels play crucial roles in various physiological processes, including pain perception, sensory signaling, and cellular response to acidosis.
| Catalog Number | C000121 |
| CAS Number | 1207-29-0 |
| Synonyms | 3-Amino-N-(aminoiminomethyl)-6-chloro-4,5-dihydro-5-oxo-2-pyrazinecarboxamide Hydrochloride (1:1); N-Amidino-3-amino-6-chloro-5-hydroxy-pyrazinecarboxamide Monohydrochloride |
| Molecular Formula | C₆H₇ClN₆O₂ •(HCl) |
| Purity | ≥95% |
| Solubility | DMSO (Sparingly), Methanol (Slightly) |
| Appearance | Pale Yellow to Light Yellow Solid |
| Storage | -20°C, Hygroscopic |
| Reference | Kuduk, S. D., et al.: Bioorg. Med. Chem. Lett., 19, 2514-2518 (2009) |
