5’-Deoxy-5’-methylthioadenosine

• CAT Number: R056852
• CAS Number: 2457-80-9
• Molecular Formula: C11H15N5O3S
• Molecular Weight: 297.33
• Purity: ≥95%
• Synonyms: 5’-S-Methyl-5’-thioadenosine; 5’-(Methylthio)-5’-deoxyadenosine; 5’-(Methylthio)adenosine; 5’-Deoxy(methylthio)adenosine; 5’-S-Methyl-5’-thioadenosine; 5’-S-Methylthioadenosine; NSC 335422; Vitamin L2; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-t
• Target: Apoptosis
• Solubility: Soluble in DMSO
• Storage: Store at -20℃
• IUPAC Name: (2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
• InChI: InChI=1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
• InChIKey: WUUGFSXJNOTRMR-IOSLPCCCSA-N
• SMILES: CSCC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O

5’-Deoxy-5’-methylthioadenosine (MTA) is a naturally occurring nucleoside involved in the methionine salvage pathway and polyamine biosynthesis. Formed as a byproduct during the synthesis of polyamines like spermidine and spermine, MTA plays a critical role in cellular metabolism. It possesses anti-inflammatory, immunomodulatory, and antiproliferative properties, making it of interest in cancer research and studies on immune regulation. MTA also participates in the regulation of methylation processes and gene expression, contributing to its importance in various biological and therapeutic contexts.