5'-DMT-3'-TBDMS-Bz-rA

• CAT Number: L029314
• CAS Number: 81256-88-4
• Molecular Formula: C44H49N5O7Si
• Molecular Weight: 788.01
• Purity: ≥95%
• Target: Nucleoside Antimetabolite/Analog
• IUPAC Name: N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]purin-6-yl]benzamide
• InChI: InChI=1S/C44H49N5O7Si/c1-43(2,3)57(6,7)56-38-35(55-42(37(38)50)49-28-47-36-39(45-27-46-40(36)49)48-41(51)29-14-10-8-11-15-29)26-54-44(30-16-12-9-13-17-30,31-18-22-33(52-4)23-19-31)32-20-24-34(53-5)25-21-32/h8-25,27-28,35,37-38,42,50H,26H2,1-7H3,(H,45,46,48,51)/t35-,37-,38-,42-/m1/s1
• InChIKey: QNPRMZLAAWKAPQ-GNECSJIWSA-N
• SMILES: CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

5′-DMT-3′-TBDMS-Bz-rA(CAT: L029314) is a protected ribonucleoside derivative widely used in oligonucleotide synthesis and nucleic acid research. Featuring a 5′-dimethoxytrityl (DMT) group and a 3′-tert-butyldimethylsilyl (TBDMS) group for stability and selective deprotection, along with a benzoyl (Bz) modification on the adenine base, this compound ensures precise and efficient synthesis of RNA sequences. Its robust design supports applications in therapeutic RNA development, molecular biology studies, and the creation of modified nucleotides. 5′-DMT-3′-TBDMS-Bz-rA is an essential building block for researchers advancing RNA-based technologies and exploring innovative nucleic acid chemistries.