5-Fluoro Uridine

• CAT Number: R000107
• CAS Number: 316-46-1
• Molecular Formula: C9H11FN2O6
• Molecular Weight: 262.19
• Purity: ≥95%
• Synonyms: 5-FUrd; NSC 146604; NSC 519273
• Target: Apoptosis
• Storage: -20°C
• IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
• InChI: InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
• InChIKey: FHIDNBAQOFJWCA-UAKXSSHOSA-N
• SMILES: C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)F

5-Fluoro uridine（Cat No.:R000107）is a nucleoside analog where a fluorine atom is substituted at the 5′ position of the uridine base. It is used in biochemical research to study RNA metabolism and function. As a uridine derivative, 5-fluoro uridine can be incorporated into RNA, where it alters normal RNA processing and inhibits RNA synthesis by disrupting the function of RNA polymerase. It has potential applications in cancer research, particularly for targeting rapidly proliferating cells, as well as in antiviral therapy. Its use is also explored in the synthesis of modified RNA for experimental studies.