5-Fluoroanthranilic Acid

For research use only. Not for therapeutic Use.

  • CAT Number: R001241
  • CAS Number: 446-08-2
  • Molecular Formula: C7H6FNO2
  • Molecular Weight: 155.128
  • Purity: ≥95%
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2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for <em>TRP1</em>, a commonly used genetic marker in <em>S. cerevisiae</em>. Because this <em>trp1</em> strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to 2-amino-5-fluorobenzoic acid feedback inhibition, enabling a growth-based, positive selection of the <em>TRP1</em> marker. 2-Amino-5-fluorobenzoic acid is frequently used in genetic procedures that involve plasmid manipulations.


Catalog Number R001241
CAS Number 446-08-2
Synonyms

2-Amino-5-fluorobenzoic Acid, 5-FAA

Molecular Formula C7H6FNO2
Purity ≥95%
Storage -20°C
IUPAC Name 2-amino-5-fluorobenzoic acid
InChI InChI=1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey FPQMGQZTBWIHDN-UHFFFAOYSA-N
SMILES C1=CC(=C(C=C1F)C(=O)O)N

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