5-Formyl-2'-deoxyuridine

• CAT Number: L037965
• CAS Number: 4494-26-2
• Molecular Formula: C10H12N2O6
• Molecular Weight: 256.21
• Purity: ≥95%
• IUPAC Name: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde
• InChI: InChI=1S/C10H12N2O6/c13-3-5-2-12(10(17)11-9(5)16)8-1-6(15)7(4-14)18-8/h2-3,6-8,14-15H,1,4H2,(H,11,16,17)/t6-,7+,8+/m0/s1
• InChIKey: MVORBLZUGBSUNB-XLPZGREQSA-N
• SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C=O)CO)O

5-Formyl-2′-deoxyuridine（Cat No.:L037965）is a modified nucleoside derived from thymidine, characterized by the presence of a formyl group at the 5-position of the uracil ring. It is used in biochemical research to study DNA damage, repair mechanisms, and the effects of oxidative stress on nucleic acids. This compound can be incorporated into DNA, where it may cause mutations or disruptions in normal base pairing, making it valuable for understanding DNA stability and replication. Its applications extend to cancer research and the development of novel therapeutic strategies targeting DNA modifications.