5-Glutinen-3β-ol

• CAT Number: R002212
• CAS Number: 545-24-4
• Molecular Formula: C30H50O
• Molecular Weight: 426.73
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: (3S,6aS,6aS,6bR,8aR,12aR,14aR,14bS)-4,4,6a,6b,8a,11,11,14a-octamethyl-1,2,3,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydropicen-3-ol
• InChI: InChI=1S/C30H50O/c1-25(2)13-14-27(5)15-17-29(7)22-11-9-20-21(10-12-24(31)26(20,3)4)28(22,6)16-18-30(29,8)23(27)19-25/h9,21-24,31H,10-19H2,1-8H3/t21-,22+,23-,24+,27-,28+,29-,30+/m1/s1
• InChIKey: HFSACQSILLSUII-ISSAZSKYSA-N
• SMILES: CC1(CCC2(CCC3(C4CC=C5C(C4(CCC3(C2C1)C)C)CCC(C5(C)C)O)C)C)C

5-Glutinen-3β-ol（Cat No.:R002212）, also known as 5-hydroxycholesterol, is a sterol intermediate in the biosynthesis of steroid hormones and bile acids. It is formed from lanosterol through a series of enzymatic reactions, primarily in the endoplasmic reticulum of hepatocytes. 5-Glutinen-3β-ol is a precursor to various biologically active compounds, including 5,6-epoxycholesterol, which plays a role in the regulation of cholesterol homeostasis and as a ligand for the liver X receptors (LXRs). LXRs are nuclear receptors that control the expression of genes involved in cholesterol metabolism, inflammation, and lipid homeostasis.