For research use only. Not for therapeutic Use.
5′-Guanidinonaltrindole hydrochloride（Cat No.:I010386）is a selective ligand and inhibitor of the kappa-opioid receptor (KOR), a G-protein coupled receptor involved in regulating pain, mood, and stress responses. It is a modified form of naltrindole, a well-known KOR antagonist, with the addition of a guanidine group that enhances its binding affinity and selectivity for the receptor. This compound is primarily used in pharmacological research to investigate the role of KOR in various physiological processes, including analgesia, addiction, and neuroprotection. Its specificity makes it a valuable tool for studying KOR-related disorders and therapeutic interventions.
| CAS Number | 351183-88-5 |
| Synonyms | 2-[(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-7-yl]guanidine;dihydrochloride |
| Molecular Formula | C27H31Cl2N5O3 |
| Purity | ≥95% |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
