5-Hydroxymatrine

• CAT Number: R029259
• CAS Number: 3411-37-8
• Molecular Formula: C15H24N2O2
• Molecular Weight: 264.37
• Purity: ≥95%
• Synonyms: 5-Hydroxy-matridin-15-one; Sophoranol; (+)-5α-Hydroxymatrine; (+)-Sophoranol; [7aR-(7aα,13aβ,13bα,13cα)]-Dodecahydro-7a-hydroxy-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]naphthyridin-10-one
• Target: HBV
• Storage: -20°C
• IUPAC Name: (1R,2R,9R,17R)-9-hydroxy-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
• InChI: InChI=1S/C15H24N2O2/c18-13-6-1-5-12-11-4-2-8-16-9-3-7-15(19,14(11)16)10-17(12)13/h11-12,14,19H,1-10H2/t11-,12-,14-,15-/m1/s1
• InChIKey: VQYBAEAOOJBSTR-QHSBEEBCSA-N
• SMILES: C1C[C@@H]2[C@H]3CCCN4[C@H]3[C@@](CCC4)(CN2C(=O)C1)O

5-Hydroxymatrine（Cat No.:R029259）is a bioactive alkaloid derived from the traditional Chinese medicinal plant Sophora flavescens. It exhibits a wide range of pharmacological activities, including anti-inflammatory, antiviral, and anticancer properties. By modulating key signaling pathways, such as NF-κB and MAPK, it reduces inflammation and inhibits tumor growth. Its antiviral potential has been demonstrated against hepatitis viruses and other pathogens. Additionally, 5-hydroxymatrine shows promise in protecting liver function and managing fibrotic diseases. Its diverse biological effects make it a significant compound in medicinal chemistry and therapeutic research.