5-LOX-IN-2

• CAT Number: I040951
• CAS Number: 179691-97-5
• Molecular Formula: C17H16O4
• Molecular Weight: 284.31
• Purity: ≥95%
• Synonyms: 2-phenylethyl (E)-3-(2,5-dihydroxyphenyl)prop-2-enoate
• InChI: InChI=1S/C17H16O4/c18-15-7-8-16(19)14(12-15)6-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-6+
• InChIKey: OQKRMXDGEFRBAJ-RMKNXTFCSA-N
• SMILES: C1=CC=C(C=C1)CCOC(=O)C=CC2=C(C=CC(=C2)O)O

5-LOX-IN-2(CAT: I040951) is a potent inhibitor of 5-lipoxygenase (5-LOX), with an IC50 of 0.33 μM. It inhibits 5-LOX in a dose-dependent manner, interfering with the production of leukotrienes, which are involved in inflammation and cancer progression. 5-LOX-IN-2 has shown significant anticancer activity by reducing cell viability and inducing apoptosis in renal cancer cells. This makes it a promising candidate for Cancer Disease Research, where it can be utilized to explore novel therapeutic strategies targeting the 5-LOX pathway in cancer treatment.