5-Methoxycarbonylmethyl-2'-O-methyluridine

• CAT Number: I041247
• CAS Number: 60197-31-1
• Molecular Formula: C13H18N2O8
• Molecular Weight: 330.29
• Purity: ≥95%
• Synonyms: methyl 2-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate
• InChI: InChI=1S/C13H18N2O8/c1-21-8(17)3-6-4-15(13(20)14-11(6)19)12-10(22-2)9(18)7(5-16)23-12/h4,7,9-10,12,16,18H,3,5H2,1-2H3,(H,14,19,20)/t7-,9+,10?,12-/m1/s1
• InChIKey: XOTXNXXJZCFUOA-RQRPQDJZSA-N
• SMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)CC(=O)OC)CO)O

5-Methoxycarbonylmethyl-2′-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Reference

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.
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